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Angelicae Fructus. Angelica Fruit. Angelicae Radix. Angelica Root.

ANGELICAE FRUCTUS.
ANGELICA FRUIT.

Angelica fruit is the product of Archangelica officinalis, Hoffm. (N.O. Umbelliferae), a biennial plant indigenous to Northern Europe and Asia, but cultivated for medicinal use in Thuringia and elsewhere. The dried fruits are yellowish, oval, about 7 millimetres long, 5 millimetres wide, and strongly compressed dorsally. The three dorsal ridges are prominent and bluntly keeled, and the two lateral extended to form membranous margins. The mericarps are usually separate—a brown seed lying loose in the cavity of each. The transverse section of the pericarp is divisible into an outer portion which is free from vittae, and an inner portion containing about twenty vittae in each mericarp. The drug has an aromatic odour, and aromatic, slightly bitter taste.

Constituents.—Angelica fruit yields about 1 per cent. of volatile oil (specific gravity, 0.856 to 0.900; [α]D = +11 to +12), the only known constituents of which are phellandrene and esters of rnethylethyl-acetic (valeric) and oxymyristic acids.

Action and Uses.—The properties of angelica fruit resemble those of angelica root. It is used in the preparation of Tinctura Antiperiodica.


ANGELICAE RADIX.
ANGELICA ROOT.

Angelica root is obtained from Archangelica officinalis, Hoffm. (N.O. Umbelliferae), a biennial plant indigenous to Northern Europe and Asia, but cultivated for medicinal use in Thuringia and elsewhere. The drug consists of a short rhizome about 6 centimetres thick, to which the remains of leaves are attached, and from which numerous greyish-brown roots from 20 to 30 centimetres long and from 0.5 to 1.0 centimetre thick proceed, the latter being often plaited or twisted together. The root breaks with a short fracture and exhibits in transverse section a broad cortex, in which numerous radially arranged yellowish-brown oleoresin ducts are to be seen. The wood is radiate, the wood rays being finely porous and narrower than the white medullary rays. The drug possesses a strong aromatic odour and taste. The root of wild angelica, Angelica sylvestris, Linn., a common British plant, is less branched and much less aromatic than that of Archangelica officinalis.

Constituents.—The chief constituents of angelica root are volatile oil (0.3 to 1.0 per cent.), resin (6.0 per cent.), angelic acid and a phytosterol (angelicol). The volatile oil has a specific gravity, 0.857 to 0.918; it contains phellandrene and other terpenes, together with a sesquiterpene and esters of methyl -ethyl -acetic (valeric) and oxypentadecylic acids; the chief odorous constituent is in the portion of higher boiling-point.

Action and Uses.—Angelica root is used as a stimulating expectorant, being administered either in the form of powder, or as infusion (1 in 20).

Dose.—6 to 20 decigrams (10 to 30 grains).


The British Pharmaceutical Codex, 1911, was published by direction of the Council of the Pharmaceutical Society of Great Britain.



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