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National Formulary Elixirs.

Preparations:

In the following pages will be found formulae from the National Formulary, for those most important. For more extensive lists the reader is referred to the National Formulary, and Elixirs, by J. U. Lloyd.

National Formulary Elixirs.—ELIXIR AMMONII BROMIDI (N. F.), Elixir of ammonium bromide.—Formulary number, 32: "Ammonium bromide, eighty-five grammes (85 Gm.) [3 oz. av.]; citric acid, four grammes (4 Gm.) [62 grs.]; aromatic elixir (U. S. P.), a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Dissolve the ammonium bromide and the citric acid in about five hundred cubic centimeters (500 Cc.) [16 fl℥, 435♏] of aromatic elixir, by agitation. Then add enough aromatic elixir to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏], and filter, if necessary. Each fluid drachm contains 5 grains of ammonium bromide"—(Nat. Form).

ELIXIR AMMONII VALERIANATIS (N. F.), Elixir of ammonium valerianate.—Formulary number, 33: "Ammonium valerianate, thirty-five grammes (35 Gm.) [1 oz. av., 103 grs.]; chloroform, eight-tenths of a cubic centimeter (0.8 Cc.) [13♏]; tincture of vanilla (U. S. P.), sixteen cubic centimeters (16 Cc.) [260♏]; compound tincture of cudbear (F. 419), sixteen cubic centimeters (16 Cc.) [260♏]; water of ammonia (U. S. P.), aromatic elixir (U. S. P.), of each, a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Dissolve the ammonium valerianate in about seventy-five cubic centimeters (75 Cc.) [2 fl℥, 257♏] of aromatic elixir, in a graduated vessel, and add enough water of ammonia, in drops, until a faint excess of it is perceptible in the liquid. Then add the chloroform, tincture of vanilla and compound tincture of cudbear and finally, enough aromatic elixir to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Filter, if necessary. Each fluid drachm contains 2 grains of ammonium valerianate. Note.—Should the odor of valerianic acid become perceptible after the elixir has been kept for some time, it may be overcome by slightly supersaturating with water of ammonia"—(Nat. Form.).

ELIXIR APII GRAVEOLENTIS COMPOSITUM (N. F.), Compound elixir of celery.—Formulary number, 36: "Fluid extract of celery seed (F. 139), sixty-two cubic centimeters (62 Cc.) [2 fl℥, 46♏]; fluid extract of erythroxylon (U. S. P.), sixty-two cubic centimeters (62 Cc.) [2 fl℥, 46♏]; fluid extract of kola (F. 175), sixty-two cubic centimeters (62 Cc.) [2 fl℥, 46♏]; fluid extract of viburnum prunifolium (U. S. P.), sixty-two cubic centimeters (62 Cc.) [2 fl℥, 46♏]; alcohol, one hundred and twenty-five cubic centimeters (125 Cc.) [4 fl℥, 109♏]; aromatic elixir (U. S. P.), a sufficient quantity, to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Mix the alcohol with two hundred and fifty cubic centimeters (250 Cc.) [8 fl℥, 218♏] of aromatic elixir. To this add the fluid extract of celery seed in several portions, shaking after each addition, and afterwards the other fluid extracts. Finally add enough aromatic elixir to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏], allow the mixture to stand 24 hours, and filter. Note.—If this preparation is prescribed or quoted under its Latin title, it is recommended that the full title be given, so that the word 'Apii' may not be mistaken for 'Opii'"—(Nat. Form.).

ELIXIR BISMUTHI (N. F.), Elixir of bismuth.—Formulary number, 37: "Bismuth and ammonium citrate, thirty-five grammes (35 Gm.) [1 oz. av., 103 grs.]; water, hot, sixty cubic centimeters (60 Cc.) [9 fl℥, 14♏]; water of ammonia (U. S. P.), and aromatic elixir (U. S. P.), of each a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Dissolve the bismuth and ammonium citrate in the hot water, allow the solution to stand until any undissolved matter has subsided; then decant the clear liquid, and add to the residue just enough water of ammonia to dissolve it. Then mix it with the decanted portion and add enough aromatic elixir to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Filter, if necessary. Each fluid drachm represents 2 grains of bismuth and ammonium citrate"—(Nat. Form).

ELIXIR BUCHU (N. F.), Elixir of buchu.—Formulary number, 38: "Fluid extract of buchu (U. S. P.), one hundred and twenty-five cubic centimeters (125 Cc.) [4 fl℥, 109♏]; alcohol, sixty-two cubic centimeters (62 Cc.) 12 fl℥, 46♏]; syrup (U. S. P.), sixty-two cubic centimeters (62 Cc.) [2 fl℥, 46♏]; magnesium carbonate, fifteen grammes (15 Gm.) [231 grs.]; aromatic elixir (U. S. P.), a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Mix the fluid extract of buchu with the alcohol, then add seven hundred and fifty cubic centimeters (750 Cc.) [25 fl℥, 173♏], of aromatic elixir, and the syrup. Incorporate with it the magnesium carbonate, and filter. Finally, pass enough aromatic elixir through the filter to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Each fluid drachm represents about 71 grains of buchu"—(Nat. Form.).

ELIXIR BUCHU COMPOSITUM (N. F.), Compound elixir of buchu.—Formulary number, 39: "Compound fluid extract of buchu (F. 144), two hundred and fifty cubic centimeters (250 Cc.) [8 fl℥, 218♏]; alcohol, sixty-two cubic centimeters (62 Cc.) [2 fl℥, 46♏]; syrup (U. S. P.), sixty-two cubic centimeters (62 Cc.) [2 fl℥, 46♏]; magnesium carbonate, fifteen grammes (15 Gm.) [231 grs.]; aromatic elixir (U. S. P.), a sufficient quantity to make one thousand cubic centimeters (1000 Cc. [33 fl℥, 391♏]. Mix the compound fluid extract of buchu with the alcohol, then add five hundred cubic centimeters (500 Cc.) [16 fl℥, 435♏] of aromatic elixir, and the syrup. Incorporate with it the magnesium carbonate, and filter. Finally, pass enough aromatic elixir through the filter to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Each fluid drachm represents 15 minims of compound fluid extract of buchu"—(Nat. Form.).

ELIXIR BUCHU ET POTASSII ACETATIS (N. F.), Elixir of buchu and potassium acetate.—Formulary number, 40: "Potassium acetate, eighty-five grammes (85 Gm.) ozs. av.]; elixir of buchu (F. 38), a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Dissolve the potassium acetate in about seven hundred and fifty cubic centimeters (750 Cc.) [25 fl℥, 173♏] of elixir of buchu; filter, if necessary, and add enough elixir of buchu to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Each fluid drachm represents 5 grains of potassium acetate and about 7 grains of buchu"—(Nat. Form.).

ELIXIR CAFFEINAE (N. F.), Elixir of caffeine.—Formulary number, 41: "Caffeine, seventeen and one-half grammes (17.5 Gm.) [270 grs.]; diluted hydrobromic acid E 8. P.), four cubic centimeters (4 Cc.) [65♏]; syrup of coffee (F. 367), two hundred and fifty cubic centimeters (250 Cc.) [8 fl℥, 218♏]; aromatic elixir (U. S. P.), a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Rub the caffeine, in a mortar, with the diluted hydrobromic acid, and about one hundred and twenty-five cubic centimeters (125 Cc.) [4 fl℥, 109♏] of aromatic elixir, until solution is effected. Then add the syrup of coffee, and lastly, enough aromatic elixir to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Filter, if necessary. Each fluid drachm contains 1 grain of caffeine"—(Nat. Form.).

ELIXIR CALCII HYPOPHOSPHITIS (N. F.), Elixir of calcium hypophosphite.—Formulary number, 43: "Calcium hypophosphite, thirty-five grammes (35 Gm.) [1 oz. av., 103 grs.]; citric acid, four grammes (4 Gm.) [62 grs.]; aromatic elixir (U. S. P.), a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Dissolve the calcium hypophosphite in nine hundred cubic centimeters (900 Cc.) [30 fl℥, 308♏] of aromatic elixir, and filter. Dissolve the citric acid in the filtrate, and pass enough aromatic elixir through the filter to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Each fluid drachm contains 2 grains of calcium hypophosphite"—(Nat. Form.).

ELIXIR CALCII LACTOPHOSPHATIS (N. F.), Elixir of calcium lactophosphate.—Formulary number, 44: "Calcium lactate, seventeen and one-half grammes (17.5 Gm.) [270 grs.]; phosphoric acid (U. S. P., 85 per cent), eight cubic centimeters (8 Cc.) [130♏]; water, sixty cubic centimeters (60 Cc.) [2 fl℥, 14♏]; syrup (U. S. P.), sixty cubic centimeters (60 Cc.) [2 fl℥, 14♏]; aromatic elixir (U. S. P.), a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Triturate the calcium lactate with the phosphoric acid, the water, and the syrup, until the salt is dissolved. Then add enough aromatic elixir to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏], and filter. Each fluid drachm represents 1 grain of calcium lactate, or about 1 1/2 grains of so-called calcium lactophosphate"—(Nat. Form.).

ELIXIR CATHARTICUM COMPOSITUM (N. F.), Compound cathartic elixir.—Formulary number, 45: "Fluid extract of senna (U. S. P.), one hundred and twenty-five cubic centimeters (125 Cc.) [4 fl℥, 109♏]; fluid extract of podophyllum (U. S. P.), sixty-two cubic centimeters (62 Cc.) [2fl℥, 46♏]; fluid extract of leptandra (U.S. P.), fifty cubic centimeters (50 Cc.) [1 fl℥, 332♏]; fluid extract of jalap (F. 162), fifty cubic centimeters (50 Cc.) [1 fl℥, 332♏]; potassium and sodium tartrate, one hundred and twenty-five grammes (125 Gm.) [4 ozs. av., 179 grs.]; sodium bicarbonate, sixteen grammes (16 Gm.) [247 grs.]; compound elixir of taraxacum (F. 111), two hundred and fifty cubic centimeters (250 Cc.) [8 fl℥, 218♏]; elixir of glycyrrhiza (F. 76), a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Mix the fluid extracts with the compound elixir of taraxacum; in the mixture dissolve the salts by agitation, and add enough elixir of glycyrrhiza to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. The product should not be filtered, and should be shaken up whenever any of it is dispensed. The average dose for an adult is 2 fluid drachms"—(Nat. Form.).

ELIXIR CHLOROFORMI COMPOSITUM (N. F.), Compound elixir of chloroform.—Formulary number, 46: "Chloroform, one hundred and ninety cubic centimeters (190 Cc.) [6 fl℥, 204♏]; tincture of opium (U.S. P.), one hundred and ninety cubic centimeters (190 Cc.) [6 fl℥, 204♏]; spirit of camphor (U. S. P.), one hundred and ninety cubic centimeters (190 CC.) [6 fl℥, 204♏]; aromatic spirit of ammonia (U. S. P.), one hundred and ninety cubic centimeters (190 Cc.) [6 fl℥, 204♏]; alcohol, two hundred and thirty-five cubic centimeters (23 Cc.) [7 fl℥, 454♏]; oil of cinnamon (cassia), five cubic centimeters (5 Cc.) [81♏]. Mix the chloroform with the alcohol, then add the oil of cinnamon, aromatic spirit of ammonia, spirit of camphor, and tincture of opium. Allow the mixture to stand a few hours, and filter in a well-covered funnel. Each fluid drachm represents about 1 grain of opium and 11 minims of chloroform. Note.—This preparation is called chloroform paregoric in some sections of the country. It is recommended that this title be abandoned, to prevent confusion with the official paregoric or Tinctura Opii Camphorata"—(Nat. Form.).

ELIXIR CINCHONAE (N. F.), Elixir of cinchona, Elixir of calisaya.—Formulary number, 47: "Tincture of Cinchona (U. S. P.), one hundred and fifty cubic centimeters (150 Cc.) [5 fl℥, 35♏]; syrup (U. S. P.), one hundred and twenty-five cubic centimeters (125 Cc.) [4 fl℥, 109♏]; glycerin, one hundred and twenty-five cubic centimeters (125 Cc.) [4 fl℥, 109♏]; aromatic elixir (U. S. P.),six hundred cubic centimeters (600 Cc.) [20 fl℥, 138♏]. Mix the liquids, allow to stand as long as convenient, and filter through a wetted filter. Each fluid ounce represents about 14 grains of yellow cinchona"—(Nat. Form.).

ELIXIR CINCHONAE DETANNATUM (N. F.), Detannated elixir of cinchona, Detannated elixir of calisaya.—Formulary number, 48: "Detannated tincture of cinchona (F. 403), one hundred and fifty cubic centimeters (150 Cc.) [5 fl℥, 35♏]; syrup (U. S. P.), one hundred and twenty-five cubic centimeters (125 Cc.) [4 fl℥, 109♏]; glycerin, one hundred and twenty-five cubic centimeters (125 Cc.) [4 fl℥, 109♏]; aromatic elixir (U. S. P.), six hundred cubic centimeters (600 Cc.) [20 fl℥, 138♏]. Mix the liquids, and filter, if necessary. Each fluid ounce represents about fourteen grains (14 grains) of yellow cinchona. Note.—This preparation may be used when elixir cinchonae is directed. in combination with preparations of iron, but may be replaced by compound elixir of quinine (F. 98), colored by the addition of fifteen cubic centimeters (15 Cc.) [242♏] of compound tincture of cudbear (F. 419) to one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]"—(Nat. Form.).

ELIXIR CINCHONAE ET FERRI (N. F.), Elixir of cinchona and iron, Elixir of calisaya and iron, Ferrated elixir of calisaya.—Formulary number, 50: "Phosphate of iron (U. S. P.), thirty-five grammes (35 Gm.) [1 oz. av., 103 grs.]; water, boiling, sixty cubic centimeters (60 Cc.) [2 fl℥, 14♏]; compound elixir of quinine. (F. 98), a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Dissolve the phosphate of iron in the boiling water, then add enough compound elixir of quinine to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏], and filter. Each fluid drachm contains 2 grains of phosphate of iron"—(Nat. Form).

ELIXIR CINCHONAE, FERRI ET STRYCHNINAE (N. F.), Elixir of cinchona, iron and strychnine, Elixir of calisaya, iron and strychnine.—Formulary number, 55: "Strychnine sulphate, one hundred and seventy-five milligrammes (0.175 Gm.) [2.7 grs.]; water, fifteen cubic centimeters (15 Cc.) [242♏]; elixir of cinchona and iron (F. 50), a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Dissolve the strychnine sulphate in the water and add enough elixir of cinchona and iron to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Each fluid drachm contains 1/100 grain of strychnine sulphate, and about 2 grains of phosphate of iron"—(Nat. Form.).

ELIXIR CURASSAO (N. F.), Elixir of curacao, Curacao cordial.—Formulary number, 58: "Spirit of curacao (F. 348), sixteen cubic centimeters (16 Cc.) [260♏]; orris root, in fine powder, four grammes (4 Gm.) [62 grs.]; deodorized alcohol, two hundred and fifty cubic centimeters (250 Cc.) [8 fl℥, 218♏]; citric acid, seven grammes (7 Gm.) [108 grs.]; syrup (U. S. P.), five hundred cubic centimeters (500 Cc.) [16 fl℥, 435♏]; magnesium carbonate, fifteen grammes (15 Gm.) [231 grains]; water, a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Mix the spirit of curacao with the alcohol, add the orris root, the magnesium carbonate, and one hundred and eighty-five cubic centimeters (185 Cc.) [6 fl℥, 123♏] of water. Allow the mixture to stand 12 hours, occasionally agitating; then pour it on a wetted filter, returning the first portions of the filtrate until it runs through clear, and pass enough water through the filter to make the filtrate measure five hundred cubic centimeters (500 Cc.) [16 fl℥, 435♏]. In this dissolve the citric acid, and finally add the syrup"—(Nat. Form.).

ELIXIR ERYTHROXYLI (N. F.), Elixir of erythroxylon, Elixir of coca.—Formulary number, 61: "Fluid extract of erythroxylon (U. S. P.), one hundred and twenty-five cubic centimeters (125 Cc.) [4 fl℥, 109♏]; alcohol, sixty-two and one-half cubic centimeters (62.5 Cc.) [2 fl℥, 54♏]; syrup (U. S. P.) one hundred and twenty-five cubic centimeters (125 Cc.) [4 fl℥, 109♏]; tincture of vanilla (U. S. P.), sixteen cubic centimeters (16 Cc.) [260♏]; purified talcum (F. 395), fifteen grammes (15 Gm.) [231 grs.]; aromatic elixir (U. S. P.), a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Mix the fluid extract with the alcohol, the syrup and six hundred and fifty cubic centimeters (650 Cc.) [21 fl℥, 470♏] of aromatic elixir, add the purified talcum and incorporate the latter thoroughly. Let the mixture stand during 48 hours, if convenient, shaking occasionally; then filter, add the tincture of vanilla to the filtrate, and pass enough aromatic elixir through the filter to make the product measure one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Each fluid drachm represents 7 1/2 grains of erythroxylon (coca)"—(Nat. Form.).

ELIXIR FERRI HYPOPHOSPHITIS (N. F.), Elixir of hypophosphite of iron.—Formulary number, 65: "Solution of hypophosphite of iron (F. 219), one hundred cubic centimeters (100 Cc.) [3 fl℥, 183♏]; aromatic elixir (U. S. P.), nine hundred cubic centimeters (900 Cc.) [30 fl℥, 208♏]. Mix, allow the mixture to stand a few days in a cool place, and filter, if necessary. Each fluid drachm contains 1 grain of hypophosphite of iron (ferric)"—(Nat. Form.).

ELIXIR FERRI PHOSPHATIS (N. F.), Elixir of phosphate of iron.—Formulary number, 67. Phosphate of iron (U. S. P.) thirty-five grammes (35 Gm.) [1 oz. av., 103♏]; water, sixty cubic centimeters (60 Cc.) [2 fl℥, 14♏]; aromatic elixir (U. S. P.), a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Dissolve the phosphate of iron in the water with the aid of heat; then mix this solution with a sufficient quantity of aromatic elixir to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Filter, if necessary. Each fluid drachm contains 2 grains of phosphate of iron"—(Nat. Form.).

ELIXIR FERRI PHOSPHATIS, QUININAE ET STRYCHNINAE (N. F.), Elixir of phosphate of iron, quinine and strychnine.—Formulary number, 69: "Phosphate of iron (U. S. P.), seventeen and one-half grammes (17.5 Gm.) [270 grs.]; quinine (alkaloid), eight and three-fourths grammes (8.75 Gm.) [135 grs.]; strychnine (alkaloid), two hundred and seventy-five milligrammes (0.275 Gm.) [4.24 grs.]; alcohol, one hundred and thirty cubic centimeters (130 Cc.) [4 fl℥, 190♏]; water, fifty cubic centimeters (50 Cc.) [1 fl℥, 332♏]; aromatic elixir (U. S. P.), a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Dissolve the alkaloids in the alcohol and add seven hundred and fifty cubic centimeters (750 Cc.) [25 fl℥, 173♏] of aromatic elixir, then dissolve the phosphate of iron in the water, using heat, if necessary, and add to the previous mixture. Finally, add enough aromatic elixir to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Each fluid drachm contains 1 grain of phosphate of iron, 1/2 grain of quinine, and 1/64 grain of strychnine. Note.—When this elixir is mixed with water, it may become cloudy or opaque through the separation of some of its constituents"—(Nat. Form.).

ELIXIR FERRI PYROPHOSPHATIS (N. F.), Elixir of pyrophosphate of iron.—Formulary number, 70: "Pyrophosphate of iron (U. S. P.), thirty-five grammes (35 Gm.) [1 oz. av., 103 grs.]; water, sixty cubic centimeters (60 Cc.) [2 fl℥, 14♏]; aromatic elixir (U. S. P.), a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Dissolve the pyrophosphate of iron in the water, and add enough aromatic elixir to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Filter, if necessary. Each fluid drachm contains 2 grains of pyrophosphate of iron"—(Nat. Form.).

ELIXIR FERRI, QUININAE ET STRYCHNINAE (N. F.), Elixir of iron, quinine and strychnine.—Formulary number, 71: "Tincture of citro-chloride of iron (F. 407), one hundred and twenty-five cubic centimeters (125 Cc.) [4 fl℥, 109♏]; quinine hydrochlorate, eight and one-half grammes (8.5 Gm.) [131 grs.]; strychnine sulphate, one hundred and seventy-five milligrammes (0.175 Gm.) [2.7 grs.]; alcohol, thirty cubic centimeters (30 Cc.) [1 fl℥, 7♏]; aromatic elixir (U. S. P.), a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Dissolve the alkaloidal salts in about seven hundred and fifty cubic centimeters (750 Cc.) [25 fl℥, 173♏] of aromatic elixir, then add the tincture and the alcohol, and finally, enough aromatic elixir to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Filter, if necessary. Each fluid drachm represents about 1 grain of ferric chloride, 1 grain of quinine hydrochlorate, and grain of strychnine sulphate"—(Nat. Form.).

ELIXIR FRANGULAE (N. F.), Elixir of frangula, Elixir of buckthorn.—Formulary number, 72: "Fluid extract of frangula (U. S. P.), two hundred and fifty cubic centimeters (250 Cc.) [8 fl℥, 218♏]; alcohol, sixty cubic centimeters (60 Cc.) [2 fl℥, 14♏]; compound elixir of taraxacum (F. 111), two hundred and fifty cubic centimeters (250 Cc.) [8 fl℥, 218♏]; aromatic elixir (U. S. P.), four hundred and forty cubic centimeters (440 Cc.) [14 fl℥, 422♏]. Mix them, allow the mixture to stand during 48 hours, if convenient, and filter. Each fluid drachm represents 15 grains of frangula"—(Nat. Form.).

ELIXIR GENTIANAE (N. F.), Elixir of gentian.—Formulary number, 73: "Fluid extract of gentian (U. S. P.), thirty-five cubic centimeters (35 Cc.) [1 fl℥, 88♏]; compound spirit of cardamom (F. 347), twenty-five cubic centimeters (25 Cc.) [406♏]; solution of tersulphate of iron (U. S. P.), twenty-five cubic centimeters (25 Cc.) [406♏]; water of ammonia (U. S. P.), twenty-eight cubic centimeters (28 Cc.) [455♏]; alcohol, water, aromatic elixir (U. S. P.), of each, a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Dilute the solution of tersulphate of iron with two hundred and fifty cubic centimeters (250 Cc.) [8 fl℥, 218♏] of cold water, and add it, constantly stirring, to the water of ammonia, previously diluted with an equal volume of cold water. Collect the precipitate on a well wetted muslin strainer, allow it to drain completely, return it to the vessel, mix it intimately with two hundred and fifty cubic centimeters (260 Cc.) [8 fl℥, 218♏] of water, and again drain. Repeat this operation once more with the same quantity of water. When the precipitate has been completely drained for the third time, fold the strainer, and press it gently so as to remove the water as completely as possible without loss of magma; then remove the magma into a tared bottle, and ascertain its weight. Now, add to the magma one-fifth (1/5) of its weight of alcohol, the fluid extract, the compound spirit, and seven hundred and fifty cubic centimeters (750 Cc.) [25 fl℥, 173♏] of aromatic elixir, and shake the mixture occasionally during 24 hours. Filter through paper, and pass enough aromatic elixir through the filter to make the product measure one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Each fluid drachm represents about 2 grains of gentian"—(Nat. Form.).

ELIXIR GENTIANAE CUM TINCTURA FERRI CHLORIDI (N. F.), Elixir of gentian with tincture of chloride of iron.—Formulary number, 74: "Tincture of citro-chloride of iron (F. 407), one hundred cubic centimeters (100 Cc.) [3 fl℥, 183♏]; elixir of gentian (F. 73), nine hundred cubic centimeters (900 Cc.) [30 fl℥, 208♏]. Mix and filter, if necessary. Each fluid drachm represents about 3/4 grain of ferric chloride, and nearly 2 grains of gentian"—(Nat. Form.).

ELIXIR GLYCYRRHIZAE AROMATICUM (N. F.), Aromatic elixir of glycyrrhiza, Aromatic elixir of liquorice.—Formulary number, 77: "Fluid extract of glycyrrhiza (U. S. P.), one hundred and twenty-five cubic centimeters (125 Cc.) [4 fl℥, 109♏]; oil of cloves, four-tenths of a cubic centimeter (0.4 Cc.) [6.5♏]; oil of cinnamon (Ceylon), four-tenths of a cubic centimeter (0.4 Cc.) [6.5♏]; oil of nutmegs, one-fourth of a cubic centimeter (0.25 Cc.) [4♏]; oil of fennel, three-fourths of a cubic centimeter (0.75 Cc.) [12♏]; magnesium carbonate, fifteen grammes (15 Gm.) [231 grs.]; aromatic elixir (U. S. P.), a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Triturate the oils with magnesium carbonate, and gradually add eight hundred and seventy-five cubic centimeters (875 Cc.) [29 fl℥, 282♏] of aromatic elixir. Shake occasionally during an hour, filter, and pass enough aromatic elixir through the filter to make eight hundred and seventy-five cubic centimeters (875 Cc.) [29 fl℥, 282♏] of filtrate. Add the fluid extract to the filtrate, mix, and filter, if necessary"—(Nat. Form.). Employed to mask the bitterness of quinine.

ELIXIR GUARANAE (N. F.), Elixir of guarana.—Formulary number, 79: "Fluid extract of guarana (U. S. P.), two hundred cubic centimeters (200 Cc.) [6 fl℥, 366♏]; aromatic elixir (U. S. P.), two hundred cubic centimeters (200 Cc.) [6 fl℥, 366♏]; compound elixir of taraxacum (F. 111), six hundred cubic centimeters (600 Cc.) [20 fl℥, 138♏]. Mix them; allow the mixture to stand during 48 hours, if convenient, and filter. Each fluid drachm represents about 12 grains of guarana"—(Nat. Form.).

ELIXIR HYPOPHOSPHITUM (N. F.), Elixir of Hypophosphites.—Formulary number, 81: "Calcium hypophosphite, fifty-two and one-half grammes (52.5 Gm.) [1 oz. av., 373 grs.]; sodium hypophosphite, seventeen and one-half grammes (17,5 Gm.) [270 grs.]; potassium hypophosphite, seventeen and one-half grammes (17.5 Gm.) [270 grs.]; citric acid, four grammes (4 Gm.) [62 grs.]; water, two hundred and fifty cubic centimeters (250 Cc.) [8 fl℥, 218♏]; glycerin, thirty cubic centimeters (30 Cc.) [1 fl℥, 7♏]; compound spirit of cardamom (F. 347), thirty cubic centimeters (30 Cc.) [1 fl℥, 7♏]; aromatic elixir (U. S. P.), a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Dissolve the hypophosphites and the citric acid in the water; then add the glycerin, compound spirit of cardamom, and enough aromatic elixir to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Filter, if necessary. Each fluid drachm contains 3 grains of calcium hypophosphite and 1 grain each of sodium and potassium hypophosphite"—(Nat. Form.).

ELIXIR HYPOPROSPHITUM CUM FERRO (N. F.), Elixir of hypophosphites with iron.—Formulary number, 82: "Calcium hypophosphite, twenty-five grammes (95 Gm.) [386 grs.]; sodium hypophosphite, seventeen and one-half grammes (17.5 Gm.)[270 grs.]; potassium hypophosphite, eight and one-half grammes (8,5 Gm.) [131 grs.]; sulphate of iron, in clear crystals, thirteen grammes (13 Gm.) [201 grs.]; citric acid, four grammes (4 Gm.) [62 grs.]; water, two hundred and fifty cubic centimeters (250 Cc.) [8 fl℥, 218♏]; syrup (U. S. P.), two hundred and fifty cubic centimeters (250 Cc.) [8 fl℥, 218♏]; aromatic elixir (U. S. P.), a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Dissolve the hypophosphites in one hundred and seventy-five cubic centimeters (175 Cc.) [5 fl℥, 440♏] of water, and add the syrup. Dissolve the sulphate of iron in the remainder of the water, and mix this with the other solution. Then add three hundred and fifty cubic centimeters (350 Cc.) [11 fl℥, 401♏] of aromatic elixir, set the mixture aside, in a cold place for 12 hours, and filter from the deposited calcium sulphate. Finally, dissolve the citric acid in the filtrate, and pass enough aromatic elixir through the filter to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Each fluid drachm contains about 1/2 grain of hypophosphite of iron (ferrous), about 1 grain each, of the hypophosphites of calcium and sodium, and 1/2 grain of potassium hypophosphite"—(Nat. Form.).

ELIXIR LITHII CITRATIS (N. F.), Elixir of lithium citrate.—Formulary number, 84: "Lithium citrate, eighty-five grammes (85 Gm.) [3 oz. av.]; aromatic elixir (U. S. P.), a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Dissolve the lithium citrate in about nine hundred cubic centimeters (900 Cc.) [30 fl℥, 208♏] of aromatic elixir, by agitation. Then add enough aromatic elixir to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏], and filter. Each fluid drachm contains 5 grains of lithium citrate"—(Nat. Form.).

ELIXIR MALTI ET FERRI (N. F.), Elixir of malt and iron.—Formulary number, 86: "Extract of malt, two hundred and fifty cubic centimeters (250 Cc.) [8 fl℥, 218♏]; phosphate of iron (U. S. P.), seventeen and one-half grammes (17.5 Gm.) [270 grs.]; water, thirty cubic centimeters (30 Cc.) [1 fl℥, 7♏]; aromatic elixir (U. S. P.), a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Dissolve the phosphate of iron in the water by the aid of heat, mix the solution with the extract of malt previously introduced into a graduated bottle, and add enough aromatic elixir to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Set the mixture aside for 24 hours, and filter. Each fluid drachm represents 1 grain of phosphate of iron, and 15 minims of extract of malt. Note.—Extract Of malt, most suitable for this preparation, should have about the consistence of Balsam, of Peru, at a temperature of about 15° C. (59° F.)"—(Nat. Form.).

ELIXIR PEPSINI (N. F.), Elixir of pepsin.—Formulary number, 88: "Pepsin (U. S. P.), seventeen and one-half grammes (17.5 Gm.) [270 grs.]; hydrochloric acid (U. S. P.), four cubic centimeters (4 Cc.) [65♏]; glycerin, one hundred and twenty-five cubic centimeters (125 Cc.) [4 fl℥, 109♏]; compound elixir of taraxacum (F. 111), sixty-five cubic centimeters (65 Cc.) [2 fl℥, 95♏]; alcohol, one hundred and seventy-five cubic centimeters (175 Cc.) [5 fl℥, 441♏]; purified talcum (F. 395), fifteen grammes (15 Gm.) [231 grs.]; sugar, two hundred and fifty grammes (250 Gm.) [8 ozs. av., 358 grs.]; water, a sufficient quantity, to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Mix the pepsin with three hundred and fifty cubic centimeters (350 Cc.) [11 fl℥, 401♏] of water, add the glycerin and acid, and agitate until solution has been effected. Then add the compound elixir of taraxacum, alcohol, and the purified talcum, and mix thoroughly. Set the mixture aside for a few hours, occasionally agitating. Then filter it through a wetted filter, dissolve the sugar in the filtrate, and pass enough water through the filter to make the whole product measure one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Each fluid drachm represents 1 grain of pepsin"—(Nat. Form.).

ELIXIR PEPSINI, BISMUTHI ET STRYCHNINAE (N. F.), Elixir of pepsin, bismuth and strychnine.—Formulary number, 89: "Strychnine sulphate, one hundred and seventy-five milligrammes (0.175 Gm.) [2.7 grs.]; elixir of pepsin and bismuth (F. 90), one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Dissolve the strychnine sulphate in the elixir. Each fluid drachm represents 1/100 grain of strychnine sulphate, 1 grain of pepsin, and 2 grains of bismuth and ammonium citrate"—(Nat. Form.). This execrable combination, in a pharmaceutical sense, has been one of the most popular American elixirs. Possibly, its chief advantage rests in the minute amount of strychnine present, and the fact that the incompatible nature of the pepsin and bismuth precipitates the former and destroys the latter.

ELIXIR PEPSINI ET BISMUTHI (N. F.), Elixir of pepsin and bismuth.—Formulary number, 90: Pepsin (U. S. P.), seventeen and one-half grammes (17.5 Gm.) [270 grs.]; bismuth and ammonium. citrate, thirty-five grammes (35 Gm.) [1 oz. av., 103 grs.]; water of ammonia (U. S. P.), a sufficient quantity; glycerin, one hundred and twenty-five cubic centimeters (125 Cc.) [4 fl℥, 109♏]; alcohol, one hundred and seventy-five cubic centimeters (175 Cc.) [5 fl℥, 441♏]; syrup (U. S. P.), two hundred and fifty cubic centimeters (250 Cc.) [8 fl℥, 218♏]; compound elixir of taraxacum, (F. 111), sixty-five cubic centimeters (65 Cc.) [2 fl℥, 95♏]; purified talcum, (F. 395), fifteen grammes (15 Urn.) [937 grs.]; water, a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Dissolve the pepsin in two hundred and fifty cubic centimeters (250 Cc.) [8 fl℥, 218♏] of water. Dissolve the bismuth and ammonium citrate in sixty cubic centimeters (60 Cc.) [2 fl℥, 14♏] of warm water, allow the solution to stand until clear, if necessary; then decant the clear liquid, and add to the residue just enough water of ammonia to dissolve it, carefully avoiding an excess. Then mix the two solutions, and add the glycerin, compound elixir of taraxacum, and alcohol. Thoroughly incorporate the purified talcum with the mixture, filter it through a wetted filter, and pass enough water through the filter to make the filtrate measure seven hundred and fifty cubic centimeters (750 Cc.) [25 fl℥, 173♏]. To this add the syrup. Each fluid drachm represents 1 grain of pepsin, and 2 grains of bismuth and ammonium citrate"—(Nat. Form.).

ELIXIR POTASSII ACETATIS ET JUNIPERI (N. F.), Elixir of potassium acetate and Juniper.—Formulary number, 96: "Potassium acetate, eighty-five grammes (85 Gm.) [3 ozs. av.]; fluid extract of juniper (F. 164), one hundred and twenty-five cubic centimeters (125 Cc.) [4 fl℥, 109♏]; magnesium carbonate, fifteen grammes (15 Gm.) [231 grs.]; aromatic elixir (U. S. P.), a sufficient quantity, to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Triturate the fluid extract of juniper with the magnesium carbonate, then add seven hundred and fifty cubic centimeters (750 Cc.) [25 fl℥, 173♏] of aromatic elixir in which the potassium acetate has previously been dissolved. Filter, and add enough aromatic elixir through the filter, to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Each fluid drachm represents 5 grains of potassium acetate and 7 1/2 grains of juniper"—(Nat. Form.).

ELIXIR RHAMNI PURSHIANAE (N. F.), Elixir rhamnus purshiana, Elixir of cascara sagrada.—Formulary number, 101: "Fluid extract of rhamnus purshiana (U. S. P.), two hundred and fifty cubic centimeters (250 Cc.) [8 fl℥, 218♏]; compound elixir of taraxacum (F. 111), seven hundred and fifty cubic centimeters (750 Cc.) [25 fl℥, 173♏]. Mix them. Allow the mixture to stand a few days, if convenient, and filter. Each fluid drachm represents 15 grains of rhamnus purshiana"—(Nat. Form.).

ELIXIR RHEI (N. F.), Elixir of rhubarb.—Formulary number, 103: "Sweet tincture of rhubarb (U. S. P.), five hundred cubic centimeters (500 Cc.) [16 fl℥, 435♏]; deodorized alcohol, sixty-five cubic centimeters (65 Cc.) [2 fl℥, 95♏]; water, one hundred and eighty-five cubic centimeters (185 Cc) [6 fl℥, 123♏]; glycerin, one hundred and twenty-five cubic centimeters (125 Cc.) [4 fl℥, 109♏]; syrup (U. S. P.), one hundred and twenty-five cubic centimeters (125 Cc.) [4 fl℥, 109♏]. Mix them and filter. Each fluid drachm represents about 21 grains of rhubarb"—(Nat. Form.).

ELIXIR RUBI COMPOSITUM (N. F.), Compound elixir of blackberry.—Formulary number, 105: "Blackberry root, one hundred and sixty grammes (160 Gm.) [5 ozs. av., 282 grs.]; galls, one hundred and sixty grammes (160 Gm.) [5 ozs. av., 282 grs.]; cinnamon, Saigon, one hundred and sixty grammes (160 Gm.) [5 ozs. av., 282 grs.]; cloves, forty grammes (40 Gm.) [1 oz. av., 180 grs.]; mace, twenty grammes (20 Gm.) [309 grs.]; ginger, twenty grammes (20 Gm.) [309 grs.]; blackberry juice, recently expressed, thirty-seven hundred and fifty cubic centimeters (3750 Cc.) [126 fl℥,385♏]; syrup (U. S. P.), eighteen hundred and seventy-five cubic centimeters (1875 Cc.) [63 fl℥, 192♏]; glycerin, eighteen hundred and seventy-five cubic centimeters (1875 Cc.) [63 fl℥, 192♏]; diluted alcohol (U. S. P.), a sufficient quantity to make ten thousand cubic centimeters (10,000 Cc.) [16 O, 82 fl℥, 66♏]. Reduce the solids to a moderately coarse (No. 40) powder, moisten it with diluted alcohol, and percolate it with this menstruum in the usual mariner, until twenty-five hundred cubic centimeters (2500 Cc.) [84 fl℥, 257♏] of percolate are obtained. To this add the blackberry juice, syrup, and glycerin, and mix thoroughly"—(Nat. Form.)

ELIXIR SODII SALICYLATIS (N. F.), Elixir of sodium salicylate.—Formulary number, 108:"Sodium salicylate, eighty-five grammes (85 Gm.) [3 ozs. av.]; aromatic elixir (U. S. P.), a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Dissolve the sodium salicylate in about eight hundred cubic centimeters (800 Cc.) [27 fl℥, 25♏] of aromatic elixir, by agitation. Then add enough aromatic elixir to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏], and filter, if necessary. This preparation should be freshly prepared, when required for use. Each fluid drachm contains 5 grains of sodium salicylate"—(Nat. Form.).


King's American Dispensatory, 1898, was written by Harvey Wickes Felter, M.D., and John Uri Lloyd, Phr. M., Ph. D.



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