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Fluidextractum Hyoscyami. U. S. Fluidextract of Hyoscyamus.

Botanical name:

Fldext. Hyosc. [Fluidextract of Henbane]

Related entries: Hyoscyamus

"One hundred mils of Fluidextract of Hyoscyamus yields not less than 0.055 Gm. nor more than 0.075 Gm. of the alkaloids of hyoscyamus." U. S.

Extrait liquide de Jusquiame, Fr.; Flüssiges Bilsenkrautextrakt, G.

"Hyoscyamus, in No. 40 powder, one thousand grammes [or 35 ounces av., 120 grains]. Prepare a Fluidextract by Type Process A (see page 483), using a mixture of three volumes of alcohol and one volume of water as the menstruum. After dissolving the soft extract in the reserve liquid, assay a portion as directed below, and, from the result thus obtained, ascertain by calculation the amount of alkaloids in the remainder of the liquid and dilute this with enough menstruum to make each one hundred mils of the finished Fluidextract contain 0.065 Gm. of the alkaloids of hyoscyamus." U. S.

"Assay.—Proceed as directed under Fluidextractum Belladonna Radicis, modifying the process there given by using 25 mils of the Fluidextract of Hyoscyamus in place of 10 mils of fluidextract of belladonna root, and before titrating treating the residue twice with 5 mils of ether and evaporating to dryness each time.

"Each .mil of tenth-normal sulphuric acid V.S. consumed corresponds to 28.92 milligrammes of the total alkaloids of hyoscyamus." U. S.

The menstruum for this fluidextract was improved in the revision of the U. S. Pharmacopoeia IX by increasing the alcoholic strength to alcohol 3, water 1. It is of a very dark greenish-brown color. For the medicinal properties, see Hyoscyamus.

Dose, from three to ten minims (0.2-0.6 mil).


The Dispensatory of the United States of America, 1918, was edited by Joseph P. Remington, Horatio C. Wood and others.



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