Extractum Belladonnae Foliorum Alcoholicum. Extractum Belladonnae Radicis Fluidum.

Extractum Belladonnae Foliorum Alcoholicum (U. S. P.)—Alcoholic Extract of Belladonna Leaves.

Related entry: Belladonna.—Belladonna

SYNONYM: Extractum belladonnae alcoholicum (Pharm., 1880).

Preparation.—"Belladonna leaves, in No. 60 powder, one thousand grammes (1000 Gm.) [2 lbs. av., 3 ozs., 120 grs.]; alcohol, water, each, a sufficient quantity. Mix two thousand cubic centimeters (2000 Cc.) [67 fl℥, 301♏] of alcohol with one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏] of water, and, having moistened the powder with four hundred cubic centimeters (400 Cc.) [13 fl℥, 252♏] of the mixture, pack it firmly in a cylindrical percolator; then add enough menstruum to saturate the powder and leave a stratum above it. When the liquid begins to drop from the percolator, close the lower orifice, and, having closely covered the percolator, macerate for 48 hours. Then allow the percolation to proceed, gradually adding menstruum, using the same proportions of alcohol and water as before, until three thousand cubic centimeters (3000 Cc.) [101 fl℥, 212♏] of tincture are obtained, or the belladonna leaves are exhausted. Reserve the first nine hundred cubic centimeters (900 Cc.) [30 fl℥, 208♏] of the percolate, evaporate the remainder at a temperate not exceeding 50° C. (122° F), to one hundred cubic centimeters (100 Cc.) [3 fl℥, 183♏], mix the residue with the reserved portion, and evaporate at or below the above-mentioned temperature to a pilular Consistence"—(U. S. P.).

Description, Medical Uses, and Dosage.—This extract possesses the odor and taste of belladonna, and is greenish-brown or brownish-green in color. It is used chiefly, locally, to allay pain and to control spasm. Its internal use is the same as for belladonna. The dose ranges from 1/6 to 1/3 grain, 3 times a day.


Extractum Belladonnae Radicis Fluidum (U. S. P.)—Fluid Extract of Belladonna Root.

SYNONYM: Extractum belladonnae fluidum (Pharm., 1880).

Preparation.—Belladonna root, in No. 60 powder, one thousand grammes (1000 Gm.) 12 lbs. av., 3 ozs., 120 grs.]; alcohol, water, each a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Mix eight hundred cubic centimeters (800 Cc.) [27 fl℥, 25♏] of alcohol with two hundred cubic centimeters (200 Cc.) [6 fl℥, 366♏] of water, and, having moistened the powder with three hundred and fifty cubic centimeters (350 Cc.) [11 fl℥, 401♏] of the mixture, pack it firmly in a cylindrical percolator; then add enough menstruum to saturate the powder and leave a stratum above it. When the liquid begins to drop from the percolator, close the lower orifice, and, having closely covered the percolator, macerate for 48 hours. Then allow the percolation to proceed, gradually adding menstruum, using the same proportions of alcohol and water as before, until the belladonna root is exhausted. Reserve the first nine hundred cubic centimeters (900 Cc.) [30 fl℥, 208♏] of the percolate, and evaporate the remainder at a temperature not exceeding 50° C. (122° F.), to a soft extract; dissolve this in the reserved portion, and add enough menstruum to make the fluid extract measure one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]"—(U. S. P.).

Description, Medical Uses, and Dosage.—(See Belladonna.) Fluid extract of belladonna root has a reddish-brown color. The dose ranges from 1 to 2 minims.


King's American Dispensatory, 1898, was written by Harvey Wickes Felter, M.D., and John Uri Lloyd, Phr. M., Ph. D.