Podophylli Indici Resina, I.C.A., Indian Podophyllum Resin.
Indian podophyllum resin is prepared by exhausting Indian podophyllum rhizome, in No. 40 powder, by percolation with alcohol, recovering most of the alcohol by distillation and precipitating the resin from the residual liquid by pouring it, with constant stirring, into ten times its volume of distilled water acidified with one twenty-fourth its bulk of hydrochloric acid. The mixture is allowed to stand for twenty-four hours, after which the resin is collected on a filter, washed with distilled water, and dried at a temperature not exceeding 37.7°. Indian podophyllum resin occurs as a bitter yellowish or brownish powder. The powder should not yield more than 1 per cent. of ash when incinerated.
Soluble in alcohol and in solution of ammonia, but only partly soluble in ether, and insoluble in water or acids.
Action and Uses.—Indian podophyllum resin is official in India and the Eastern Colonies, where it is used in place of ordinary podophyllum, resin, which it resembles in its properties.
Dose.—15 to 60 milligrams (1 to 1 grain). 4
- Tinctura Podophylli Indici, I.C.A.—TINCTURE OF INDIAN PODOPHYLLUM.
- Indian podophyllum resin, 3.65; alcohol, sufficient to produce 100. Macerate the resin with 90 of alcohol for twenty-four hours, with occasional agitation; then filter, and pass sufficient alcohol through the filter to make up to the required volume. Tincture of Indian podophyllum is official in India and the Eastern Colonies for use in place of Tinctura Podophylli. Dose.—3 to 10 decimils (0.3 to 1.0 milliliters) (5 to 15 minims).
The British Pharmaceutical Codex, 1911, was published by direction of the Council of the Pharmaceutical Society of Great Britain.