Tinctura Cannabis. U. S. (Br.). Tincture of Cannabis.
Tr. Cannab. [Tinctura Cannabis Indicae, U.S.P. VIII]
"When assayed biologically Tincture of Cannabis produces incoordination when administered to dogs in a dose of not more than 0.3 mil per kilogramme of body weight." U. S.
Tinctura Cannabis Indicae, Br.; Tincture of Indian Hemp; Tincture of Hemp; Teinture (alcoole) de Chanvre de I'lnde, Fr. Cod.; Indischhanftinktur, G.
"Cannabis, in No. 40 powder, one hundred grammes [or 3 ounces av., 231 grains]; to make about one thousand mils [or 33 fluidounces, 6 1/2 fluidrachms]. Prepare a Tincture by Type Process P, as modified for assayed tinctures, using alcohol as the menstruum, and adjusting the volume of the finished Tincture to conform with the above biological standard." U. S.
"Extract of Indian Hemp, 50 grammes; Alcohol (90 per cent.) sufficient to produce 1000 millilitres. Dissolve." Br.
"Assay.—Proceed as directed under Biological Assays." U. S. (Also see Cannabis).
Tincture of cannabis is assayed by tests upon dogs and it is generally advisable, for this purpose, to concentrate the tincture to about one-fourth its bulk. Care should be observed in the process of evaporation that the temperature does not rise above 60° C. (140° F.).
The American reader must take care not to confound the Indian Hemp here referred to with Apocynum cannabinum, known by the same name in this country. The term "Indian Hemp" should be dropped entirely, as its continued use has been the cause of at least one fatal mistake. The strength of the present tincture is about 33 per cent. less than that of the 1890 tincture.
Dose, ten to thirty minims (0.6-1.8 mils), to be gradually increased until some effects are experienced.
Off. Prep.—Tinctura Chloroformi et Morphinae Composita, Br. Mistura Chloroformi et Morphinae Composita. N. F.
Related entry: Cannabis
The Dispensatory of the United States of America, 1918, was edited by Joseph P. Remington, Horatio C. Wood and others.