Extractum Stramonii Exsiccatum, B.P.C. Dried Extract of Stramonium.
Related entries: Stramonium
Synonyms.—Extractum Stramonii Foliorum Exsiccatum; Dried Extract of Stramonium Leaves.
|Stramonium Leaves, in No. 40 powder||100.00|||||20 ounces|
|Alcohol (70 per cent.), a sufficient quantity.|
Moisten the drug with 40 (8 fluid ounces) of the alcohol, pack in a percolator, and percolate till 400 (80 fluid ounces) are obtained. Press the marc, mix the liquids, and filter. Assay the filtrate for dry extract and for alkaloid. Having thus ascertained the amount of extract that the remainder of the filtrate will yield and the amount of alkaloid that will be contained in it, calculate the quantity of powdered stramonium leaves of known alkaloidal value that must be added to reduce the alkaloidal value of the extract to 1 per cent. Add rather less than this quantity of powdered leaves to the remainder of the filtrate. Recover the alcohol by distillation, and dry the residue in a current of warm air from 60° to 80° until the weight is fairly constant. Calculate the additional weight of diluent required, and add to the product. Transfer the whole to a warm mortar, triturate until well mixed, and pass through a No. 20 sieve. Dried extract of stramonium must be kept in well-stoppered bottles, and stored in a cool, dry place. The extract is hygroscopic, and to counteract this it is desirable to use as diluent a powdered leaf of such high alkaloidal content that the finished product will contain at least two of diluent to one of extract.
Dose.—15 to 60 milligrams (1/4 to 1 grain).
The British Pharmaceutical Codex, 1911, was published by direction of the Council of the Pharmaceutical Society of Great Britain.