Fluidextractum Grindelia. U. S. (Br.)
Fluidextract of Grindelia. Fldext. Grindel.
Related entries: Grindelia
Preparations: Fluidextract of Grindelia
Extractum Grindeliae Liquidum, Br., Liquid Extract of Grindelia; Extrait liquide de Grindelia, Fr.; Flüssiges Grindelienextrakt, G.
"Grindelia, in No. 30 powder, one thousand grammes [or 35 ounces av., 120 grains]. Prepare a Fluidextract by Type Process A, using a mixture of three volumes of alcohol and one volume of water as the menstruum." U. S. "Grindelia, in No. 40 powder, 1000 grammes; Sodium Bicarbonate, 100 grammes; Distilled Water, 500 millilitres; Alcohol (90 per cent.), sufficient to produce 1000 millilitres. Exhaust the Grindelia by percolation with the Alcohol. Recover the alcohol from the percolate by distillation, and dissolve the residue in the Distilled Water, to which the Sodium Bicarbonate has previously been added; after effervescence has ceased, add sufficient Distilled Water to produce seven hundred and fifty millilitres, and then sufficient of the Alcohol to produce the required volume." Br.
This is a fluidextract which well represents the drug; owing to the large quantity of resinous matter present, it does not mix well with aqueous liquids. The so-called "alkaline fluid extract of grindelia" may be made by evaporating one pint of official fluidextract until reduced to twelve fluidounces, making a solution of 180 grains of sodium bicarbonate in four fluidounces of water, adding it slowly to the evaporated fluidextract, and filtering; the British liquid extract is made upon this principle. The fluidextract is a dark brown liquid having the peculiar odor of grindelia.
For medical properties and uses, see Grindelia.
Dose, from one-half to one fluidrachm (1.8-3.75 mils).