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Quininae Hydriodidum Acidum. Acid Quinine Hydriodide.

Related entries: Quinine - Red Cinchona Bark

C20H26N2O2I2, 5H2O = 670.148.

Synonyms.—Quininae Iodidum Acidum; Acid Quinine Iodide.

Acid quinine hydriodide, C20H24N2O2, 2HI, 5H2O, maybe prepared by adding a solution of potassium iodide to a warm solution of quinine in diluted sulphuric acid, and crystallising. It occurs in the form of yellowish crystals or scales. On heating, the crystals become opaque at 30° and melt at 100° in their water of crystallisation, becoming completely anhydrous at 120°. When the anhydrous salt is exposed to a damp atmosphere it takes up two molecules of water. The salt contains 48.4 per cent. of quinine. It should be protected from light.

Soluble in water (1 in 20).

Action and Uses.—Acid quinine hydriodide has been used for similar purposes to Quininae Hydriodidum.

Dose.—1/2 to 3 decigrams (1 to 5 grains).

PREPARATION.

Syrupus Quininae Hydriodidi, B.P.C.—SYRUP OF QUININE HYDRIODIDE. Syn.—Syrup of Iodide of Quinine.
Contains 1 grain of acid quinine hydriodide in 1 fluid drachm. Dose.—2 to 4 mils (1/2 to 1 fluid drachm).

The British Pharmaceutical Codex, 1911, was published by direction of the Council of the Pharmaceutical Society of Great Britain.



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