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Mistura Copaibae Composita.—Compound Copaiba Mixture.

Related entry: Copaiba (U. S. P.)—Copaiba

SYNONYM: Diuretic drops.

Preparation.—Take of spirit of nitrous ether and oil of almonds, each, 1 fluid ounce; copaiba and oil of turpentine, of each, 1/2 fluid ounce; camphor, in powder, 10 grains. Mix the liquids, then add the camphor, and agitate briskly (Beach's Amer. Prac.).

Action, Medical Uses, and Dosage.—This forms a diuretic mixture, which has been successfully and extensively used in gonorrhoea, gleet, scalding of urine, and urinary affections. The dose is 1 fluid drachm three times a day, in some tea or mucilage. It should be well agitated previous to administration.

Other Copaiba Mixtures.—There are various mixtures of copaiba in use for the cure of gonorrhoea, and as several of them have been found efficient, I give the formulas for preparing them:

  1. Take of copaiba, spirit of nitrous ether, compound spirit of lavender, tincture of chloride of iron, of each, 1 fluid ounce. Mix. The dose is a teaspoonful three times a day.
  2. Take of oil of cubebs, oil of anise, copaiba, tincture of opium, tincture of chloride of iron, of each, 1 fluid ounce. Mix. The dose is a teaspoonful three times a day. The foregoing preparations are very disagreeable to the taste, but very efficient in gonorrhoea, after the active symptoms have subsided. They must be agitated thoroughly previous to taking each dose, and in order to protect the teeth from the injurious action of the acid in the tincture of iron, it is recommended to rinse the mouth immediately after taking each dose, with a solution of bicarbonate of potassium.
  3. Take of solidified copaiba, 2 ounces; white wax, 1 ounce; oil of cubebs, oil of spearmint, of each, 1 fluid drachm; niter, finely pulverized, 2 drachms. Melt the wax, add the oils, and then the copaiba; stir all well together, and, finally, add the niter. This forms a paste once used for the cure of gonorrhoea. The dose is a quantity about the size of a small chestnut, three times a day.
  4. Take of alum, in powder, 1 drachm; precipitated carbonate of iron, 1/2 ounce; pulverized cubebs, 1 ounce; copaiba, a sufficient quantity to form a kind of paste. The dose is the same as in the preceding reparation (J. King).

MISTURA COPAIBAE COMPOSITA (N. F.), Compound copaiba mixture.—1. Lafayette mixture: "Copaiba, one hundred and twenty-five cubic centimeters (125 Cc.) [4 fl℥, 109♏]; spirit of nitrous ether (U. S. P.), one hundred and twenty-five cubic centimeters (125 Cc.) [4 fl℥, 109♏]; compound tincture of lavender (U. S. P), one hundred and twenty-five cubic centimeters (125 Cc.) [4 fl℥, 109♏]; solution of potassa (U. S. P.), thirty-five cubic centimeters (35 Cc.) [1 fl℥, 88♏]; syrup (U. S. P.), three hundred and twenty-five cubic centimeters (325 Cc.) [10 fl℥, 475♏]; mucilage of dextrin (F. 277), a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Mix the copaiba with the solution of potassa and the spirit of nitrous ether. Then add the compound tincture of lavender, and lastly, the syrup and mucilage of dextrin. Mix the whole thoroughly by shaking. This mixture should be well agitated whenever any of it is to be dispensed. Each fluid drachm contains 7 1/2 minims of copaiba. Note.—The above mixture has usually been, and may be, prepared with mucilage of acacia; but if mucilage of dextrin be used, it will keep for a longer time without separating. A mixture of somewhat similar composition, in considerable use in some parts of the country, is the following.

2. Chapman's mixture.—Copaiba, two hundred and fifty cubic centimeters (250 Cc.) [8 fl℥, 218♏]; spirit of nitrous ether (U. S. P.), two hundred and fifty cubic centimeters (250 Cc.) [8 fl℥, 218♏] compound tincture of lavender (U. S. P.), sixty-five cubic centimeters (65 Cc.) [2 fl℥, 95♏]; tincture of opium (U. S. P.), thirty cubic centimeters (30 Cc.) [1 fl℥, 7♏]; mucilage of acacia (U. S. P.), one hundred and twenty-five cubic centimeters (125 Cc.) [33 fl℥, 109♏]; water, a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]"—(Nat. Form).


King's American Dispensatory, 1898, was written by Harvey Wickes Felter, M.D., and John Uri Lloyd, Phr. M., Ph. D.



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