Syrup of Santonate of Soda.



A good vermifuge syrup is prepared by the following formula:

Rx. Santonate of Soda, 30 grains,
Distilled water, 1 ounce,
Syrup, 18 fluidounces.

Boil the syrup till it is concentrated to 32° Bmé. Remove from the fire, let it cool a few minutes, then add the salt dissolved in the water.

You obtain 18 fluidounces of a transparent syrup, without a bitter taste, of 35° when cold. Each fluidounce contains one grain of santonine. I have been preparing this syrup, for nine years, in the drug store of Mr. Font.

Santonate of Soda.

Rx. Santoninic Acid, in fine powder, 2 ounces.
Caustic Soda Lye, pure, 4 fluidounces
Distilled Water, 12 fluidounces.

Put all in a flask, and heat in a sand-bath, or over a stove, to 70° or 80°, until the solution of the santonine is complete, which usually requires about half an hour; then remove from the fire, and when cold it is conveniently evaporated. In cooling, prismatic crystals with an oblique base are obtained, containing 54 per ct. of santonine,

When the solution is evaporated until a strong pellicle is formed, on cooling it is converted into a mass of acicular crystals of a pearly aspect, which contain 60 per ct. of santonine.

The santonate of soda is soluble in 1 3/4 its weight of water (20° C.), and has a slightly bitter taste.

Merida, August 14, 1871.

The American Journal of Pharmacy, Vol. XLIII, 1871, was edited by William Procter, Jr. (Issues 1-4) and John M. Maisch (Issues 5-12).