Extractum Belladonnae Radicis Fluidum (U. S. P.)—Fluid Extract of Belladonna Root.

Botanical name: 

Related entry: Belladonna.—Belladonna - Extractum Belladonnae Foliorum Alcoholicum (U. S. P.)—Alcoholic Extract of Belladonna Leaves.

SYNONYM: Extractum belladonnae fluidum (Pharm., 1880).

Preparation.—Belladonna root, in No. 60 powder, one thousand grammes (1000 Gm.) 12 lbs. av., 3 ozs., 120 grs.]; alcohol, water, each a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Mix eight hundred cubic centimeters (800 Cc.) [27 fl℥, 25♏] of alcohol with two hundred cubic centimeters (200 Cc.) [6 fl℥, 366♏] of water, and, having moistened the powder with three hundred and fifty cubic centimeters (350 Cc.) [11 fl℥, 401♏] of the mixture, pack it firmly in a cylindrical percolator; then add enough menstruum to saturate the powder and leave a stratum above it. When the liquid begins to drop from the percolator, close the lower orifice, and, having closely covered the percolator, macerate for 48 hours. Then allow the percolation to proceed, gradually adding menstruum, using the same proportions of alcohol and water as before, until the belladonna root is exhausted. Reserve the first nine hundred cubic centimeters (900 Cc.) [30 fl℥, 208♏] of the percolate, and evaporate the remainder at a temperature not exceeding 50° C. (122° F.), to a soft extract; dissolve this in the reserved portion, and add enough menstruum to make the fluid extract measure one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]"—(U. S. P.).

Description, Medical Uses, and Dosage.—(See Belladonna.) Fluid extract of belladonna root has a reddish-brown color. The dose ranges from 1 to 2 minims.

King's American Dispensatory, 1898, was written by Harvey Wickes Felter, M.D., and John Uri Lloyd, Phr. M., Ph. D.