Extractum Ergotae (U. S. P).—Extract of Ergot.
SYNONYMS: Ergotin, Extractum haemostaticum.
Preparation.—"Fluid extract of ergot, one hundred and fifty cubic centimeters (150 Cc.) [5 fl℥, 35♏]. Evaporate the fluid extract of ergot in a porcelain capsule, by means of a water-bath, at a temperature not exceeding 50° C. (122° F.), constantly stirring, until it is reduced to a pilular consistence"—(U. S. P.).
The British Pharmacopoeia process is based on Bonjean's. It consists in evaporating to a syrupy consistence 4 fluid ounces of liquid ergot (prepared chiefly with water), adding 4 fluid ounces of rectified spirit, filtering, and evaporating to a soft extract. This corresponds with Bonjean's Ergotin.
Description, Medical Uses, and Dosage.—(See Ergota). The U. S. P. process originated with Dr. Edward R. Squibb. The product is essentially that known as Ergotin. It is a pale-brown, or reddish-brown extract, wholly soluble in diluted alcohol, insoluble in cold alcohol, and dissolves in water, with the exception of a slight residue, yielding a garnet-red solution. Dose, 3 to 20 grains. It may be given hypodermatically by dissolving 5 parts in 7 parts each of water and glycerin, and filtering the solution.