Tinctura Conii.—Tincture of Hemlock.
Related entry: Conium (U. S. P.)—Conium
Preparation.—"Take of hemlock fruit, finely comminuted, 2 ½ ounces (av.); proof-spirit, 1 pint (Imp.)"—(Br. Pharm., 1885). Prepare as directed for Tinctura Sennae. The British Pharmacopoeia (1898) directs the use of conium fruit, recently reduced to No. 40 powder, 4 ounces (Imp.), and alcohol (70 per cent), a sufficient quantity to make 1 pint of tincture. (Modern shorthand: 1:4 70 %)
The juice of conium is considered a more effectual preparation than the preceding. The U. S. P. (1880) directed a percolated tincture of conium prepared practically as follows: TINCTURA CONII, Tincture of conium.—"Conium (fruit), in No. 30 powder, one hundred and fifty grammes (150 Gm.) [5 ozs. av., 127 grs.]; diluted hydrochloric acid, four grammes (4 Gm.) [62 grs.]; diluted alcohol, a sufficient quantity to make one thousand grammes (1000 Gm.) [2 lbs. av., 3 ozs., 120 grs.]. Moisten the powder with fifty grammes (50 Gm.) [1 oz. av., 334 grs.] of diluted alcohol, previously mixed with the diluted hydrochloric acid, and macerate for 24 hours; then pack it moderately in a conical glass percolator, and gradually pour diluted alcohol upon it, until one thousand grammes (1000 Gm.) [2 lbs. av., 3 ozs., 120 grs.] of tincture are obtained"—(Nat. Form.).
Action, Medical Uses, and Dosage.—(See Conium.) Dose, 10 to 40 minims.
