Tinctura Conii.—Tincture of Hemlock.
Related entry: Conium (U. S. P.)—Conium
Preparation.—"Take of hemlock fruit, finely comminuted, 2 ½ ounces (av.); proof-spirit, 1 pint (Imp.)"—(Br. Pharm., 1885). Prepare as directed for Tinctura Sennae. The British Pharmacopoeia (1898) directs the use of conium fruit, recently reduced to No. 40 powder, 4 ounces (Imp.), and alcohol (70 per cent), a sufficient quantity to make 1 pint of tincture. (Modern shorthand: 1:4 70 %)
The juice of conium is considered a more effectual preparation than the preceding. The U. S. P. (1880) directed a percolated tincture of conium prepared practically as follows: TINCTURA CONII, Tincture of conium.—"Conium (fruit), in No. 30 powder, one hundred and fifty grammes (150 Gm.) [5 ozs. av., 127 grs.]; diluted hydrochloric acid, four grammes (4 Gm.) [62 grs.]; diluted alcohol, a sufficient quantity to make one thousand grammes (1000 Gm.) [2 lbs. av., 3 ozs., 120 grs.]. Moisten the powder with fifty grammes (50 Gm.) [1 oz. av., 334 grs.] of diluted alcohol, previously mixed with the diluted hydrochloric acid, and macerate for 24 hours; then pack it moderately in a conical glass percolator, and gradually pour diluted alcohol upon it, until one thousand grammes (1000 Gm.) [2 lbs. av., 3 ozs., 120 grs.] of tincture are obtained"—(Nat. Form.).
Action, Medical Uses, and Dosage.—(See Conium.) Dose, 10 to 40 minims.
King's American Dispensatory, 1898, was written by Harvey Wickes Felter, M.D., and John Uri Lloyd, Phr. M., Ph. D.