Extractum Stramonii Seminis Fluidum (U. S. P.)—Fluid Extract of Stramonium Seed.
SYNONYMS: Extractum stramonii fluidum (Pharm. 1880), Fluid extract of stramonium.
Preparation.—"Stramonium seed, in No. 60 powder, one thousand grammes (1000 Gm.) [2 lbs. av., 3 ozs., 120 grs.]; alcohol, water, each, a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Mix seven hundred and fifty cubic centimeters (750 Cc.) [25 fl℥, 173♏] of alcohol with two hundred and fifty cubic centimeters (250 Cc.) [8 fl℥, 218♏] of water, and, having moistened the powder with two hundred cubic centimeters (200 Cc.) [6 fl℥, 366♏] of the mixture, pack it firmly in a cylindrical percolator; then add enough menstruum to saturate the powder and leave a stratum above it. When the liquid begins to drop from the percolator, close the lower orifice, and, having closely covered the percolator, macerate for 48 hours. Then allow the percolation to proceed, gradually adding menstruum, using the same proportions of alcohol and water as before, until the stramonium seed is exhausted. Reserve the first nine hundred cubic centimeters (900 Cc.) [30 fl℥, 208♏] of the percolate, and evaporate the remainder, at a temperature not exceeding 50° C. (122° F)., to a soft extract; dissolve this in the reserved portion, and add enough menstruum to make the fluid extract measure one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]"—(U. S. P.).
Description, Medical Uses, and Dosage.—(See Stramonium). This fluid has a deep-brown color, and, in our opinion, is improved if it be made with official, instead of diluted alcohol. In this case the color will be much lighter and the liquid will be less syrupy. The fixed oil of stramonium has no medicinal value, but nothing is gained by separating it from the drug by preliminary percolation with ether or benzol. Dose, 1/4 to 2 minims.