Extractum Frangulae Fluidum (U. S. P.)—Fluid Extract of Frangula.
Related entry: Frangula (U. S. P.)—Frangula
Preparation.—"Frangula, in No. 40 powder, one thousand grammes (1000 Gm.) [2 lbs. av., 3 ozs., 120 grs.]; alcohol, water, each a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Mix five hundred cubic centimeters (500 Cc.) [16 fl℥, 435♏] of alcohol with eight hundred cubic centimeters (800 Cc.) [27 fl℥, 25♏] of water, and, having moistened the powder with three hundred and fifty cubic centimeters (350 Cc.) [11 fl℥, 401♏] of the mixture, pack it firmly in a cylindrical percolator; then add enough menstruum to saturate the powder and leave a stratum above it. When the liquid begins to drop from the percolator, close the lower orifice, and, having closely covered the percolator, macerate for 48 hours. Then allow the percolation to proceed, gradually adding menstruum, using the same proportions of alcohol and water as before, until the frangula is exhausted. Reserve the first eight hundred cubic centimeters (800 Cc.) [27 fl℥, 25♏] of the percolate, and evaporate the remainder to a soft extract; dissolve this in the reserved portion, and add enough menstruum to make the fluid extract measure one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]"—(U. S. P.).
Description, Medical Uses, and Dosage.—(See Frangula). This preparation has a deep brownish-red color, and to the taste is both sweetish and bitter. It is an uncertain laxative. Dose, from 10 to 30 minims.