Extractum Gossypii Radicis Fluidum (N. F.)—Fluid Extract of Cotton-Root Bark.

Related entry: Gossypii Radicis Cortex (U. S. P.)—Cotton Root Bark - Extract of Gossypium

Preparation.—"Cotton-root bark, in No. 30 powder, one thousand grammes (1000 Gm.) [2 lbs. av., 3 ozs., 120 grs.]; glycerin, two hundred and fifty cubic centimeters (250 Cc.) [8 fl℥, 218♏]; alcohol, a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Mix the glycerin with seven hundred and fifty cubic centimeters (750 Cc.) [25 fl℥, 173♏] of alcohol, and, having moistened the powder with five hundred cubic centimeters (500 Cc.) [16 fl℥, 435♏] of the mixture, pack it firmly in a cylindrical percolator; then add enough menstruum to saturate the powder and leave a stratum above it. When the liquid begins to drop from the percolator, close the lower orifice, and, having closely covered the percolator, macerate for 48 hours. Then allow the percolation to proceed, gradually adding, first, the remainder of the menstruum, and then alcohol, until the cotton-root bark is exhausted. Reserve the first seven hundred cubic centimeters (700 Cc.) [23 fl℥, 321♏] of the percolate, and evaporate the remainder to a soft extract; dissolve this in the reserved portion, and add enough alcohol to make the fluid extract measure one thousand cubic centimeters (1000 Cc.) 33 fl℥, 391♏]"—(U. S. P.).

Description, Medical Uses, and Dosage.—(See Gossypium). This preparation is a bright-red fluid. It should be prepared from the recently dried root bark. Dose, ½ to 1 fluid drachm.

Gossypium fluid extract is typical of those red-tannin liquids that disintegrate spontaneously. The product is a brown magma and a watery serum. No explanation has been given for this change, which occurs without warning, and which may affect only a few bottles in a batch.

King's American Dispensatory, 1898, was written by Harvey Wickes Felter, M.D., and John Uri Lloyd, Phr. M., Ph. D.