Tinctura Kino (U. S. P.)—Tincture of Kino.
Preparation.—"Kino, one hundred grammes (100 Gm.) [3 ozs. av., 291 grs.]; glycerin, one hundred and fifty cubic centimeters (150 Cc.) [5 fl℥, 35♏]; water, two hundred cubic centimeters (200 Cc.) [6 fl℥, 366♏]; alcohol, a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Mix the glycerin with the water and six hundred and fifty cubic centimeters (650 Cc.) [21 fl℥, 470♏] of alcohol. Rub the kino, in a mortar, adding gradually a sufficient quantity of the menstruum, until a smooth paste is produced. Transfer this to a bottle, add the remainder of the menstruum, and macerate for 24 hours, with occasional agitation. Then filter through paper, adding, through the filter, enough alcohol to make the product measure one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏] Keep the tincture in small, completely-filled and well-stoppered bottles, in a cool place"—(U.S. P.). The substitution of glycerin for a portion of water was suggested by Haselden (1860) as tending to prevent gelatinization.
Action, Medical Uses, and Dosage.—Tincture of kino is astringent, and is principally used, in doses of 1 or 2 fluid drachms, in diarrhoea, cholera morbus, cholera, etc. It is frequently added to astringent mixtures (see Kino).
Related Tincture.—TINCTURA KINO COMPOSITA (N. F.), Compound tincture of kino. "Tincture of kino (U. S. P.), one hundred cubic centimeters (100 Cc.) [3 fl℥, 183♏]; tincture of opium (U. S. P.), one hundred cubic centimeters (100 Cc.) [3 fl℥, 183♏]; spirit of camphor (U. S. P.), sixty-five cubic centimeters (65 Cc.) [2 fl℥, 95♏]; oil of cloves, one and one-half cubic centimeters (1.5 Cc.) [24♏]; cochineal, in powder, nine grammes (9 Gm.) [139 grs.]; aromatic spirit of ammonia (U. S. P.), eight cubic centimeters (8 Cc.) [130♏]; diluted alcohol (U.S. P.), a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Triturate the cochineal with the aromatic spirit of ammonia, and gradually add seven hundred cubic centimeters (700 Cc.) [23 fl℥, 321♏] of diluted alcohol. Then add the two tinctures, the spirit of camphor, and the oil of cloves, and filter the mixture through paper. Lastly, pass enough diluted alcohol through the filter to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Each fluid drachm represents about ½ grain, each, of kino and of powdered opium"—(Nat. Form.).