Extractum Rhamni Purshianae Fluidum Aromaticum (N. F.)—Aromatic Fluid Extract of Rhamnus Purshiana.
SYNONYM: Aromatic fluid extract of cascara sagrada.
Preparation.—Formulary number, 173: "Rhamnus purshiana, in No. 60 powder, one thousand grammes (1000 Gm.) [2 lbs. av., 3 ozs., 120 grs.]; glycyrrhiza, in No. 40 powder, one hundred grammes (100 Gm.) [3 ozs. av., 231 grs.]; calcined magnesia, one hundred and twenty-five grammes (125 Gm.) [4 ozs. av., 179 grs.]; glycerin, two hundred and fifty cubic centimeters (250 Cc.) [8 fl℥, 218♏]; compound spirit of orange (U. S. P), ten cubic centimeters (10 Cc.) [162♏]; alcohol, five hundred cubic centimeters (500 Cc.) [16 fl℥, 435♏]; water, diluted alcohol, (U. S. P.), each, a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Mix the powdered drugs and the magnesia with two thousand cubic centimeters (2000 Cc.) [67 fl℥, 301♏] of water, macerate for 12 hours and then dry the mixture on a water-bath at a gentle heat. Mix the glycerin and the alcohol with two hundred and fifty cubic centimeters (250 Cc) [8 fl℥, 218♏] of water, and percolate the dried powders with this menstruum, followed by diluted alcohol, according to the directions given under Process B (see F. 135). Reserve the first eight hundred and fifty cubic centimeters (850 Cc.) [28 fl℥, 356♏] that pass, and set this aside. Continue the percolation with diluted alcohol to practical exhaustion, evaporate this second portion to a soft extract, dissolve it in the reserved portion, and add the compound spirit of orange and sufficient diluted alcohol to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏] of fluid extract"—(Nat. Form.).
Medical Uses and Dosage.—An agreeable aromatic laxative. Dose, 10 to 45 minims.
Under the name of Cascara Cordial, Parke, Davis & Co. have long made a palatable preparation of cascara, which enjoys the confidence of those who use it. Kasagra, or Cascara Aromatica, is a liquid preparation of cascara sagrada, used extensively by physicians, made by Frederick Stearns & Co., of Detroit. Both these preparations are very pleasant to the taste, being destitute of all bitterness.