Extractum Sanguinariae Fluidum (U. S. P.)—Fluid Extract of Sanguinaria.

Related entry: Sanguinaria (U. S. P.)—Sanguinaria

SYNONYM: Fluid extract of bloodroot.

Preparation.—"Sanguinaria, in No. 60 powder, one thousand grammes (1000 Gm.) [2 lb. av., 3 ozs., 120 grs.]; acetic acid, fifty cubic centimeters (50 Cc.) [1 fl℥, 332♏]; alcohol, water, each, a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Mix the alcohol and water in the proportion of seven hundred and fifty cubic centimeters (750 Cc.) [25 fl℥, 173♏] of alcohol, and two hundred and fifty cubic centimeters (250 Cc.) [8 fl℥, 218♏] of water. Moisten the powder with three hundred cubic centimeters (300 Cc.) [10 fl℥, 69♏] of the mixture, to which the acetic acid had previously been added, and let it macerate, in a well-covered vessel, in a warm place, during 48 hours. Then pack it firmly in a cylindrical percolator, and gradually pour menstruum upon it, until the sanguinaria is exhausted. Reserve the first eight hundred and fifty cubic centimeters (850 Cc.) [28 fl℥, 356♏] of the percolate, and evaporate the remainder to a soft extract; dissolve this in the reserved portion, and add enough alcohol to make the fluid extract measure one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]"—(U. S. P.).

Description, Medical Uses, and Dosage.—(See Sanguinaria). This is a deep-red fluid with the tendency, as with all fluid preparations of bloodroot, to precipitation. The formula is improved, in this regard, by using official alcohol instead of alcohol diluted with water, and that, too, without injuring the drug energy of the product. It well represents the crude drug. Dose, from 1 to 5 minims.

King's American Dispensatory, 1898, was written by Harvey Wickes Felter, M.D., and John Uri Lloyd, Phr. M., Ph. D.