Tinctura Physostigmatis. U. S. Tincture of Physostigma. Tr. Physostig. [Tincture of Calabar Bean]
Related entries: Physostigma
"One hundred mils of Tincture of Physostigma yields not less than 0.013 Gm. nor more than 0.017 Gm. of the alkaloids of physostigma." U.S.
Teinture (alcoole) de feve du Calabar, Fr.; Kalabarbohnentinktur, G.
"Physostigma, in No. 50 powder, one hundred grammes [or 3 ounces av., 231 grains], to make about one thousand mils [or 33 fluid-ounces, 6 ½ fluidrachms]. Prepare a tincture by Type Process P, as modified for assayed tinctures, using alcohol as the menstruum and adjusting the volume of the finished tincture so that each one hundred mils contains 0.015 Gm. of the alkaloids of physostigma,
This tincture was reduced from 15 Gm. (U. S. P., 1890) to 10 Gm. of drug per 100 mils in the U. S. P. VIII and an assay process appended; the U. S. P. IX has retained this strength. This tincture of Calabar Bean is much weaker than that proposed by Fraser, which was nearly as strong as a fluidextract— five minims representing three grains of the drug.
Dose, of the official tincture, from ten to thirty minims (0.6-1.8 mils).