Tinctura Scillae. U. S., Br.

Botanical name: 

Tinctura Scillae. U. S., Br.

Tincture of Squill. Tr. Scill.

Related entries: Squill

"If assayed biologically the minimum lethal dose should not be greater than 0.006 mil of Tincture, or the equivalent in Tincture of 0.0000005 Gm. of ouabain, for each gramme of body weight of frog." U. S.

Teinture (alcoole) de Scille, Fr. Cod.; Meerzwiebeltinktur, G.; Tintura alcoholica de escila, Sp.

"Squill, in No. 20 powder, one hundred grammes [or 3 ounces av., 231 grains]; Alcohol, Water, each, a sufficient quantity, to make one thousand mils [or 33 fluidounces, 6 ½ fluidrachms]. Moisten the drug with sufficient menstruum, prepared by mixing three volumes of alcohol and one volume of water, and macerate it in a closed vessel in a moderately warm place for twenty-four hours, stirring occasionally. Then transfer it to a percolator, shake it down evenly without packing and pour on enough of the menstruum to saturate the powder and leave a stratum above it. When the liquid begins to drop from the percolator, close the lower orifice, and, having closely covered the percolator, macerate for twenty-four hours. Then allow the percolation to proceed slowly, gradually adding sufficient of the same menstruum to make one thousand mils [or 33 fluid-ounces, 6 ½ fluidrachms] of Tincture.

"Squill, bruised, 200 grammes; Alcohol (60 per cent.), 1000 millilitres. Prepare by the maceration process." Br.

Tincture of Squill was reduced from the strength of 15 Gm. (U. S. P. 1890) to 10 Gm. of drug, per 100 mils, U. S. P. VIII and IX). This tincture yields a grayish, rose-colored, very bitter and acrid deposit, consisting of silky tufts. (Meniere.) The tincture represents the virtues of squill probably better than any other official preparation.

Dose, from ten to twenty minims (0.6-1.3 mils) (from twenty to forty drops).

The Dispensatory of the United States of America, 1918, was edited by Joseph P. Remington, Horatio C. Wood and others.