Xanthium.—Guichard believes that he has found an alkaloid in the X. spinosum L. (P. J., vii, 249.) In the Xanthium Strumarium L., Cocklebur or Clotbur, which is common both in Europe and in America, A. Zander believes that he has found a glucoside, xanthostrumarin. M. V. Cheatham thinks that there is a second active principle. (See A. J. P., vol. xi, 271; vol. xiv, 134.) Clotbur is stated to be an active styptic, both local and general. Dose, of the fluidextract, from one to two fluidrachms (3.75-7.5 mils).