Mistura Camphorae Composita.—Compound Mixture of Camphor.

Botanical name: 

Related entry: Camphora (U. S. P.)—Camphor

Preparation.—Take of camphor water, peppermint water, and spearmint water, each, 1 fluid ounce; camphorated tincture of opium, 2 fluid drachms. Mix.

Action, Medical Uses, and Dosage.—This is a very efficient agent in allaying nausea and vomiting. It was extensively and successfully employed in Cincinnati in the nausea and vomiting attending Asiatic cholera. It possesses the virtues of the several articles entering into its composition, without the stimulating influence of the alcohol (which enters into their tinctures), upon already partially inflamed mucous surfaces. The dose is from a teaspoonful to a tablespoonful, every 5 minutes, if the patient be vomiting, and every 10 minutes if he be only nauseated (J. King). This preparation may be employed in painful states due to gaseous distension of the intestines.

Other Camphor and Diarrhoea Mixtures.—MISTURA CAMPHORAE ACIDA (N. F.), Acid camphor mixture, Mistura antidysenterica, Hope's mixture. "Nitric acid (U. S. P.), seventeen and one-half cubic centimeters (17.5 Cc.) [284♏]; tincture of opium (U. S. P.), twelve cubic centimeters (12 Cc.) [195♏]; camphor water (U. S. P.), a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Mix the nitric acid with about five hundred cubic centimeters (500 Cc.) [16 fl℥, 435♏] of camphor-water, add the tincture of opium, and, lastly, enough camphor water to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]"—(Nat. Form.).

MISTURA CONTRA DIARRHOEAM (N. F.), Diarrhoea mixture, Cholera mixture.—1. "Tincture of opium (U. S. P.), tincture of capsicum (U. S. P.), tincture of rhubarb (U. S. P.), spirit of camphor (U. S. P.), spirit of peppermint (U. S. P.), of each, twenty cubic centimeters (20 Cc.) [325♏]. Mix them and filter. Note.—The formula above given, which appears to be that in most general use, is also known under the name of 'Sun Mixture.' Of other similar preparations, in more or less general use, the following may be mentioned here:

2. Loomis' diarrhoea mixture.—"Tincture of opium (U. S. P.), twelve and one-half cubic centimeters (12.5 Cc.) [203♏]; tincture of rhubarb (U. S. P.), twelve and one-half cubic centimeters (12.5 Cc.) [203♏]; compound tincture of catechu (U. S. P.), twentv-five cubic centimeters (25 Cc.) [406♏]; oil of sassafras, one cubic centimeter (1 Cc.) [16♏); compound tincture of lavender (U. S. P.), forty-nine cubic centimeters (49 Cc.) [1 fl℥, 315♏].

3. Squibb's diarrhoea mixture.—"Tincture of opium (U. S. P.), twenty cubic centimeters (20 Cc.) [325♏]; tincture of capsicum (U. S. P.), twenty cubic centimeters (20 Cc.) [325♏]; spirit of camphor (U. S. P.), twenty cubic centimeters (20 Cc.) [325♏]; chloroform (U. S. P.) seven and one-half cubic centimeters (7.5 Cc.) [122♏]; alcohol, thirty-two and one-half cubic centimeters (32.5 Cc.) [1 fl℥, 47♏].

4. Thielemann's diarrhoea mixture.—"Wine of opium (U. S. P.), twenty-five cubic centimeters (25 Cc.) [406♏]; tincture of valerian (U. S. P.), thirty-seven and one-half cubic centimeters (37.5 Cc.) [1 fl℥, 129♏]; ether (U. S. P.), twelve an one-half cubic centimeters (12.5 Cc.) [203♏]; oil of peppermint, three cubic centimeters (3 Cc.) [49♏]; fluid extract of ipecac (U. S. P.), three-fourths of a cubic centimeter (0.75 Cc.) [12♏]; alcohol, twenty-one and one-fourth cubic centimeters (21.25 Cc.) [345♏]. This preparation is practically identical with the Mistura Thielemanni of the Swedish Pharm.

5. Velpeau's diarrhoea mixture.—"Tincture of opium (U. S. P.), compound tincture of catechu (U. S. P.) spirit of camphor (U. S. P.), of each, thirty-three and one-third cubic centimeters (33.33 Cc.; [1 fl℥, 61♏]"—(Nat. Form).


King's American Dispensatory, 1898, was written by Harvey Wickes Felter, M.D., and John Uri Lloyd, Phr. M., Ph. D.