Mistura Rhei et Sodae (U. S. P.)—Mixture of Rhubarb and Soda.

Botanical name: 

Related entry: Rheum (U. S. P.)—Rhubarb

Preparation.—"Sodium bicarbonate, thirty-five grammes (3,5 Gm.) [1 oz. av., 103 grs.]; fluid extract of rhubarb, fifteen cubic centimeters (15 Cc.) [243♏︎]; fluid extract of ipecac, three cubic centimeters (3 Cc.) [49♏︎]; glycerin, three hundred and fifty cubic centimeters (350 Cc.) [11 fl℥, 401♏︎]: spirit of peppermint, thirty-five cubic centimeters (35 Cc.) [1 fl℥, 88♏︎]; water, a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏︎]. Dissolve the sodium bicarbonate in about four hundred cubic centimeters (400 Cc.) [13 fl℥, 252♏︎] of water. Then add the fluid extracts, the glycerin, and the spirit of peppermint, and, lastly, enough water to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏︎]"—(U. S. P.).

Action, Medical Uses, and Dosage.—This preparation, in large doses, is purgative and carminative; in smaller amounts, it cheeks diarrhoea and colic accompanying infantile dyspepsia. Dose, ½ fluid drachms to 2 fluid ounces.

Related Preparation.—MISTURA RHEI COMPOSITA (N. F.), Compound mixture of rhubarb, Squibb's rhubarb mixture. "Fluid extract of rhubarb (U. S. P.), twelve cubic centimeters (12 Cc.) [195♏︎]; fluid extract of. ipecac (U. S. P.), two cubic centimeters (2 Cc.) [33♏︎]; sodium bicarbonate, twenty-four grammes (24 Gm.) [370 grs.]; glycerin, two hundred and fifty cubic centimeters (250 Cc.) [8 fl℥, 218♏︎]; peppermint water (U. S. P.), a sufficient quantity, to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏︎] Dissolve the sodium bicarbonate in about five hundred cubic centimeters (500 Cc.) [16 fl℥, 435♏︎] of peppermint water, then add the fluid extracts and glycerin, and lastly, enough peppermint water to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏︎]"—(Nat. Form.). This preparation must not be confused with the well-known neutralizing cordial, which in some respects it resembles.


King's American Dispensatory, 1898, was written by Harvey Wickes Felter, M.D., and John Uri Lloyd, Phr. M., Ph. D.