Tinctura Hydrastis. U. S., Br.

Botanical name: 

Tinctura Hydrastis. U. S., Br.

Tincture of Hydrastis. Tr. Hydrast. [Tincture of Golden Seal]

Related entries: Hydrastis

"One hundred mils of Tincture of Hydrastis yields not less than 0.36 Gm. nor more than 0.44 Gm. of the ether-soluble alkaloids of hydrastis." U. S.

Teinture (alcoole) de Hydrastis, Fr.; Hydrastistinktur, G.; Tintura alcoholica de hidrastis, Sp.

"Hydrastis, in No. 60 powder, two hundred grammes [or 7 ounces av., 24 grains], to make about one thousand mils [or 33 fluid-ounces, 6 ½ fluidrachms]. Prepare a Tincture by Type Process P, as modified for assayed tinctures, using a mixture of two volumes of alcohol and one volume of water as the menstruum and adjusting the volume of the finished Tincture so that each one hundred mils contains 0.4 Gm. of the ether-soluble alkaloids of hydrastis." U. S.

"Assay.—Evaporate 50 mils of Tincture of Hydrastis on a water bath until it measures about 10 mils, transfer the evaporated liquid to a separator, and proceed as directed in the assay under Fluidextractum Belladonnae Radicis, second line of the Assay, beginning with the words "add 10 mils," modifying the process there given by using the ammonia water with about 5 mils of distilled water, in divided portions, to rinse out the dish in which the Tincture was evaporated. Use only ether as the immiscible solvent throughout the assay and dry the residue at 100° C. (212° F.) to constant weight, instead of titrating it. The weight of the residue represents the amount of ether-soluble alkaloids in 50 mils of Tincture of Hydrastis." U. S.

"Liquid Extract of Hydrastis, 100 millilitres; Alcohol (60 per cent.), sufficient to produce 1000 millilitres. Mix." Br.

The British tincture is half the strength of that of the U. S. P. IX.

This tincture is useful in combination with other tinctures, or as an addition to extemporaneous mixtures where the fluidextract would not be so eligible.

Dose, from one to two fluidrachms (3.75-7.5 mils).

The Dispensatory of the United States of America, 1918, was edited by Joseph P. Remington, Horatio C. Wood and others.