Syrupus Sennae. U. S., Br. Syrup of Senna. Syr. Senn.
Sirop de Sene, Fr.; Sirupus Sennae, P. O.; Sennasirup, G.
"Fluidextract of Senna, two hundred and fifty mils [or 8 fluidounces, 218 minims]; Oil of Coriander, five mils [or 81 minims]; Syrup, a sufficient quantity, to make one thousand mils [or 33 fluidounces, 6½ fluidrachms]. Mix the oil of coriander with the fluidextract of senna and add sufficient syrup to make the product measure one thousand mils [or 33 fluidounces, 6 ½ fluidrachms]. Mix thoroughly." U. S.
"Senna Leaves, 440.0 grammes; Oil of Coriander, 0.2 millilitre; Alcohol (90 per cent.), 2.0 millilitres; Refined Sugar, 540.0 grammes; Alcohol (20 per cent), 760.0 millilitres. Moisten the Senna Leaves with four hundred and forty millilitres of the Alcohol (20 per cent.); pack tightly in a vessel which can afterwards be closed; set aside for three days; press strongly; reserve the liquid obtained; break up the marc; moisten it with one hundred and sixty millilitres of the Alcohol (20 per cent.); set aside for twenty-four hours; press strongly; add the liquid obtained to the portion previously reserved; break up the marc; mix it with the remainder of the Alcohol (20 per cent.); set aside for three hours; press again; evaporate the resulting liquid until it is reduced to such a volume that when added to the reserved liquid the whole measures four hundred and forty millilitres. Mix the evaporated liquid with the reserved liquid; heat the product in a covered vessel to 82° C. (179.6° F.) for a few minutes; set aside for twenty-four hours; filter, and pass Distilled Water through the filter until the filtrate measures four hundred and forty millilitres; add the Refined Sugar, and dissolve in a covered vessel by the aid of gentle heat; cool; add the Oil of Coriander dissolved in the Alcohol (90 per cent.); mix." Br.
The process was improved in the U S. P. VIII by simply adding the fluidextract and oil of coriander to syrup, and this process has been retained in the Ninth Revision.
Dose, of the U. S. syrup of senna, for an adult, from one to four fluidrachms (3.75-15.0 mils); of the Br. syrup from one to two fluidrachms (3.75-7.5 mils).